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Comments on the paper "High doses of riboflavin and the elimination of dietary red meat promote the recovery of some motor functions in Parkinson's disease patients. C.G. Coimbraand V.B.C. Junqueira. Brazilian Journal of Medical and Biological Research, 36: 1409-1417, 2003" BJMBR
Ferraz,H.B.; Quagliato,E.A.B.; Rieder,C.R.M.; Silva,D.J.; Teive,H.A.G.; Barbosa,E.R.; Cardoso,F.; Limongi,J.C.P.; Bezerra,J.M.F.; Andrade,L.A.F.; Allam,N.; Prado,R.C.P.; Tomas,V..
Tipo: Info:eu-repo/semantics/other Palavras-chave: Parkinson's disease; Riboflavin; FAD; Glutathione; Iron; Hemin.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2004000900002
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Delivery of riboflavin to larval and adult pacific oysters, Crassostrea gigas Thunberg by lipid spray beads ArchiMer
Langdon, Cj; Seguineau, Catherine; Ponce, B; Moal, Jeanne; Samain, Jean-francois.
Lipid spray beads (SB) were prepared containing 13% w/w particulate riboflavin. Beads suspended in seawater lost 73% riboflavin after 24 h. Release of riboflavin from SE ingested by Pacific oyster (Crassostrea gigas) larvae was observed under epifluorescent light. Riboflavin concentrations in tissues of adult oysters fed on riboflavin-SB were significantly (SNK, P < 0.05) greater than those of oysters fed on seawater-filled SE. Concentrations of riboflavin in oysters exposed to dissolved riboflavin were not significantly greater than those of oysters fed on seawater-filled SE: indicating that elevated riboflavin concentrations in oysters fed on riboflavin-SB were attributable to breakdown of ingested beads rather than uptake of dissolved riboflavin...
Tipo: Text Palavras-chave: Spray beads; Lipid; Riboflavin; Oyster; Larvae; Crassostrea gigas.
Ano: 2000 URL: http://archimer.ifremer.fr/doc/00000/10493/9511.pdf
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High doses of riboflavin and the elimination of dietary red meat promote the recovery of some motor functions in Parkinson's disease patients BJMBR
Coimbra,C.G.; Junqueira,V.B.C..
Abnormal riboflavin status in the absence of a dietary deficiency was detected in 31 consecutive outpatients with Parkinson's disease (PD), while the classical determinants of homocysteine levels (B6, folic acid, and B12) were usually within normal limits. In contrast, only 3 of 10 consecutive outpatients with dementia without previous stroke had abnormal riboflavin status. The data for 12 patients who did not complete 6 months of therapy or did not comply with the proposed treatment paradigm were excluded from analysis. Nineteen PD patients (8 males and 11 females, mean age ± SD = 66.2 ± 8.6 years; 3, 3, 2, 5, and 6 patients in Hoehn and Yahr stages I to V) received riboflavin orally (30 mg every 8 h) plus their usual symptomatic medications and all red...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Parkinson's disease; Riboflavin; Flavin-adenine dinucleotide; Glutathione; Iron; Hemin.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003001000019
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Isolation and characterization of an Ashbya gossypii mutant for improved riboflavin production BJM
Wei,Shiping; Hurley,James; Jiang,Zhenglong; Wang,Siwen; Wang,Yuanyuan.
The use of the filamentous fungus, Ashbya gossypii, to improve riboflavin production at an industrial scale is described in this paper. A riboflavin overproducing strain was isolated by ultraviolet irradiation. Ten minutes after spore suspensions of A. gossypii were irradiated by ultraviolet light, a survival rate of 5.5% spores was observed, with 10% of the surviving spores giving rise to riboflavin-overproducing mutants. At this time point, a stable mutant of the wild strain was isolated. Riboflavin production of the mutant was two fold higher than that of the wild strain in flask culture. When the mutant was growing on the optimized medium, maximum riboflavin production could reach 6.38 g/l. It has even greater promise to increase its riboflavin...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Riboflavin; Ashbya gossypii; Ultraviolet irradiation; Medium optimization.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822012000200003
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Medium composition influence on Biotin and Riboflavin production by newly isolated Candida sp BJM
Suzuki,Gaby Tiemi; Macedo,Juliana Alves; Macedo,Gabriela Alves.
Complex B vitamins as Biotin and Riboflavin are required by living organisms, not only for growth but also for metabolite production, and the feed market classifies them as growth promoters. Since Brazil will soon be one of the world's biggest animal protein producers, feed production is a large consumer of vitamins and micronutrients. The industry requires 10 mg riboflavin/0.2 mg biotin per kilogram of feed; a ratio of 40 ~ 50:1. Although few studies have been conducted specifically on riboflavin production using factorial design and surface response method as an optimization strategy, it is a common practice in biotechnology with many research reports available. However, there are no reports on the use of statistical design for biotin production. This...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Candida sp; Riboflavin; Biotin; Media development; Vitamin production.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822011000300030
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The response of young and adult rats to the riboflavin supplementation BABT
França,Camille Feitoza; Vianna,Lucia Marques.
The aim of this article was to study the response of young and adult rats on the supplementation of diet with riboflavin. Twenty-four young and adult normotensives (Wistar) male rats, subdivided into two groups: treated (10mg riboflavin/Kg of body weight) and control (receiving vehicle) were daily evaluated for physical and behavioural aspects. Systolic blood pressure was determined twice a week and liver toxicity was investigated it the end of treatment. Data were evaluated using one-way ANOVA and p<0.05 was significant. There were no changes on general health aspects of the treated rats; however, the supplementation provoked a significant (p<0.05) systolic blood pressure reduction.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Riboflavin; Antioxidant; Wistar.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132010000400015
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